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Peptide Hormone

Search Result - 1

HMRbase accession number	10006
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Melanotropin alpha 2
Mature Hormone Sequence	SYSMEHFRWGKPI
Position of mature hormone in Pre-Hormone protein	13 Residues from position (112-124)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 2

HMRbase accession number	10080
Swiss-prot Accession number	Q9PS30 (Sequence in FASTA format)
Description	Gastrin-releasing peptide (GRP).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the bombesin/neuromedin-B/ranatensin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	GRP stimulates gastrin release as well as other gastrointestinal hormones
Protein Length	23 Amino acids
Molecular weight	2479
References	1  PubMed abstract 1480521
Domain Name	N/A
Hormone Name	Gastrin-releasing peptide
Mature Hormone Sequence	SENTGAIGKVFPRGNHWAVGHLM
Position of mature hormone in Pre-Hormone protein	23 Residues from position (1-23)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	10246
Swiss-prot Accession number	Q91971 (Sequence in FASTA format)
Description	Glucagon-1 precursor (Glucagon I) [Contains: Glicentin-relatedpolypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	178 Amino acids
Molecular weight	20034
References	1  PubMed abstract 7776976
Domain Name	Hormone_2
Hormone Name	Glucagon-1
Mature Hormone Sequence	HSEGTFSNDYSKYQEERMAQDFVQWLMNS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (52-80)
Receptor	N/A
Gene ID	100136745
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 4

HMRbase accession number	10247
Swiss-prot Accession number	Q91971 (Sequence in FASTA format)
Description	Glucagon-1 precursor (Glucagon I) [Contains: Glicentin-relatedpolypeptide 1 (GRPP 1); Glucagon-1; Glucagon-like peptide 1-1 (GLP 1-1); Glucagon-like peptide 2 (GLP 2)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	178 Amino acids
Molecular weight	20034
References	1  PubMed abstract 7776976
Domain Name	Hormone_2
Hormone Name	Glucagon-like peptide 2
Mature Hormone Sequence	HVDGSFTSDVNKVLDSLAAKEYLLWVMTSKTSG
Position of mature hormone in Pre-Hormone protein	33 Residues from position (137-169)
Receptor	N/A
Gene ID	100136745
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 5

HMRbase accession number	10251
Swiss-prot Accession number	Q91189 (Sequence in FASTA format)
Description	Glucagon-2 precursor (Glucagon II) [Contains: Glicentin-relatedpolypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Promotes hydrolysis of glycogen and lipids, and raises the blood sugar level
Protein Length	178 Amino acids
Molecular weight	19998
References	1  PubMed abstract 7776976
Domain Name	Hormone_2
Hormone Name	Glucagon-2
Mature Hormone Sequence	QSEGTFSNYYSKYQEERMARDFLHWLMNS
Position of mature hormone in Pre-Hormone protein	29 Residues from position (52-80)
Receptor	N/A
Gene ID	100136748
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	10252
Swiss-prot Accession number	Q91189 (Sequence in FASTA format)
Description	Glucagon-2 precursor (Glucagon II) [Contains: Glicentin-relatedpolypeptide 2 (GRPP 2); Glucagon-2; Glucagon-like peptide 1-2 (GLP 1-2); Glucagon-like peptide 2 (GLP 2)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the glucagon family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	178 Amino acids
Molecular weight	19998
References	1  PubMed abstract 7776976
Domain Name	Hormone_2
Hormone Name	Glucagon-like peptide 2
Mature Hormone Sequence	HVDGSFTSDVNKVLDSLAAKEYLLWVMTSKTSG
Position of mature hormone in Pre-Hormone protein	33 Residues from position (137-169)
Receptor	N/A
Gene ID	100136748
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 7

HMRbase accession number	10302
Swiss-prot Accession number	P55246 (Sequence in FASTA format)
Description	Progonadoliberin-3 precursor (Progonadoliberin III) [Contains:Gonadoliberin-3 (Gonadoliberin III) (Luteinizing hormone-releasinghormone III) (LH-RH III) (Gonadotropin-releasing hormone III) (GnRHIII) (Luliberin III); GnRH-associated peptide 3 (GnRH-associatedpeptide III)] (Fragment).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the GnRH family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Stimulates the secretion of gonadotropins
Protein Length	74 Amino acids
Molecular weight	8254
References	1   Klungland H., Anderson O., Alestroem P.; "The salmon gonadotrophin-releasing hormone encoding gene insalmonids."; Mol. Mar. Biol. Biotechnol. 1:420-425(1992). 2  PubMed abstract 1308825
Domain Name	N/A
Hormone Name	Gonadoliberin-3
Mature Hormone Sequence	QHWSYGWLPG
Position of mature hormone in Pre-Hormone protein	10 Residues from position (16-25)
Receptor	Q9I986    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 8

HMRbase accession number	10309
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Corticotropin
Mature Hormone Sequence	SYSMEHFRWGKPVGRKRRPVKVYTNGVEEESSEAFPSEM
Position of mature hormone in Pre-Hormone protein	39 Residues from position (104-142)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 9

HMRbase accession number	10310
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Melanotropin alpha 1
Mature Hormone Sequence	SYSMEHFRWGKPV
Position of mature hormone in Pre-Hormone protein	13 Residues from position (104-116)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 10

HMRbase accession number	10311
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Lipotropin beta (Beta-LPH)
Mature Hormone Sequence	ELGTDDAVYPSLEAGTAEGGEAEGMEGVFSLQEKKDGSYKMNHFRWSGPPASKRYGGFMKSWDERSQKPLLTLFKNVIIKDGQQ
Position of mature hormone in Pre-Hormone protein	84 Residues from position (145-228)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 11

HMRbase accession number	10312
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Melanotropin beta 1
Mature Hormone Sequence	DGSYKMNHFRWSGPPAS
Position of mature hormone in Pre-Hormone protein	17 Residues from position (180-196)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 12

HMRbase accession number	10313
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Beta-endorphin 1
Mature Hormone Sequence	YGGFMKSWDERSQKPLLTLFKNVIIKDGQQ
Position of mature hormone in Pre-Hormone protein	30 Residues from position (199-228)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 13

HMRbase accession number	10314
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Met-enkephalin
Mature Hormone Sequence	YGGFM
Position of mature hormone in Pre-Hormone protein	5 Residues from position (199-203)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 14

HMRbase accession number	10315
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Corticotropin
Mature Hormone Sequence	SYSMEHFRWGKPIGHKRRPIKVYASSLEGGDSSEGTFPLQA
Position of mature hormone in Pre-Hormone protein	41 Residues from position (112-152)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 15

HMRbase accession number	10316
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Lipotropin beta (Beta-LPH)
Mature Hormone Sequence	QLSSWEDEMVGALGNQGAKAQTKVVPRTLTVTGLQDKKDGSYRMGHFRWGSPTAIKRYGGFMKPYTQQSHKPLITLLKHVTLKNEQ
Position of mature hormone in Pre-Hormone protein	86 Residues from position (155-240)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 16

HMRbase accession number	10317
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Lipotropin gamma (Gamma-LPH)
Mature Hormone Sequence	QLSSWEDEMVGALGNQGAKAQTKVVPRTLTVTGLQDKKDGSYRMGHFRWGSPTAI
Position of mature hormone in Pre-Hormone protein	55 Residues from position (155-209)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 17

HMRbase accession number	10318
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Melanotropin beta 2
Mature Hormone Sequence	DGSYRMGHFRWGSPTAI
Position of mature hormone in Pre-Hormone protein	17 Residues from position (193-209)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 18

HMRbase accession number	10319
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Beta-endorphin 2
Mature Hormone Sequence	YGGFMKPYTQQSHKPLITLLKHVTLKNEQ
Position of mature hormone in Pre-Hormone protein	29 Residues from position (212-240)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 19

HMRbase accession number	10341
Swiss-prot Accession number	Q91194 (Sequence in FASTA format)
Description	Somatostatin-2 precursor (Somatostatin II) [Contains: [Tyr21,Gly24]-somatostatin-28; [Tyr7,Gly10]-somatostatin-14].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the somatostatin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Somatostatin inhibits the release of somatotropin
Protein Length	115 Amino acids
Molecular weight	12963
References	1  PubMed abstract 7628684
Domain Name	Somatostatin
Hormone Name	[Tyr21,Gly24]-somatostatin-28
Mature Hormone Sequence	SVGNPNNLPPRERKAGCKNFYWKGFTSC
Position of mature hormone in Pre-Hormone protein	28 Residues from position (88-115)
Receptor	Q5G546   Detail in HMRbase    Q5G547    Detail in HMRbase
Gene ID	100136751
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 20

HMRbase accession number	10457
Swiss-prot Accession number	P33745 (Sequence in FASTA format)
Description	Pro-MCH 1 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the melanin-concentrating hormone family.
Tissue Specificity	Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modification	N/A
Function	N/A
Protein Length	132 Amino acids
Molecular weight	14608
References	1  PubMed abstract 7731499
Domain Name	N/A
Hormone Name	Neuropeptide-glutamic acid-valine
Mature Hormone Sequence	EAGQDLSPSISIV
Position of mature hormone in Pre-Hormone protein	13 Residues from position (101-113)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 21

HMRbase accession number	10458
Swiss-prot Accession number	P33745 (Sequence in FASTA format)
Description	Pro-MCH 1 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the melanin-concentrating hormone family.
Tissue Specificity	Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modification	N/A
Function	Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH
Protein Length	132 Amino acids
Molecular weight	14608
References	1  PubMed abstract 7731499
Domain Name	N/A
Hormone Name	Melanin-concentrating hormone
Mature Hormone Sequence	DTMRCMVGRVYRPCWEV
Position of mature hormone in Pre-Hormone protein	17 Residues from position (116-132)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 22

HMRbase accession number	10503
Swiss-prot Accession number	P69157 (Sequence in FASTA format)
Description	Pro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the melanin-concentrating hormone family.
Tissue Specificity	Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modification	N/A
Function	N/A
Protein Length	132 Amino acids
Molecular weight	14710
References	1  PubMed abstract 7731499
Domain Name	N/A
Hormone Name	Neuropeptide-glutamic acid-valine
Mature Hormone Sequence	EADQDLSPSISIV
Position of mature hormone in Pre-Hormone protein	13 Residues from position (101-113)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 23

HMRbase accession number	10504
Swiss-prot Accession number	P69157 (Sequence in FASTA format)
Description	Pro-MCH 2 precursor [Contains: Neuropeptide-glutamic acid-valine (NEV)(Neuropeptide E-V); Melanin-concentrating hormone (MCH)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the melanin-concentrating hormone family.
Tissue Specificity	Pituitary gland. Produced in neurons of lateral basal hypothalamus which project both to the brain and to the neural lobe of the pituitary gland from where MCH is released
Post translational modification	N/A
Function	Plays a role in skin pigmentation by antagonizing the action of melanotropin alpha. Induces melanin concentration within the melanophores. May participate in the control of the hypothalamo-pituitary adrenal gland axis by inhibiting the release of ACTH
Protein Length	132 Amino acids
Molecular weight	14710
References	1  PubMed abstract 7731499
Domain Name	N/A
Hormone Name	Melanin-concentrating hormone
Mature Hormone Sequence	DTMRCMVGRVYRPCWEV
Position of mature hormone in Pre-Hormone protein	17 Residues from position (116-132)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 24

HMRbase accession number	10713
Swiss-prot Accession number	P09538 (Sequence in FASTA format)
Description	Somatotropin 1 precursor (Growth hormone 1).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the somatotropin/prolactin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation
Protein Length	210 Amino acids
Molecular weight	23795
References	1  PubMed abstract 2908440 2  PubMed abstract 2647438 3  PubMed abstract 3545720
Domain Name	Hormone_1
Hormone Name	Somatotropin-1 (Somatotropin I) (Growth hormone I)
Mature Hormone Sequence	IENQRLFNIAVSRVQHLHLLAQKMFNDFDGTLLPDERRQLNKIFLLDFCNSDSIVSPVDKHETQKSSVLKLLHISFRLIESWEYPSQTLIISNSLMVRNANQISEKLSDLKVGINLLITGSQDGVLSLDDNDSQQLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKSLEANCTL
Position of mature hormone in Pre-Hormone protein	188 Residues from position (23-210)
Receptor	N/A
Gene ID	100136733
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 25

HMRbase accession number	10717
Swiss-prot Accession number	P20332 (Sequence in FASTA format)
Description	Somatotropin 2 precursor (Growth hormone 2).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the somatotropin/prolactin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Growth hormone plays an important role in growth control and is involved in the regulation of several anabolic processes. Implicated as an osmoregulatory substance important for seawater adaptation
Protein Length	210 Amino acids
Molecular weight	23946
References	1  PubMed abstract 2908440 2  PubMed abstract 3393535 3  PubMed abstract 2647438
Domain Name	Hormone_1
Hormone Name	Somatotropin-2 (Somatotropin II) (Growth hormone II)
Mature Hormone Sequence	MENQRLFNIAVNRVQHLHLLAQKMFNDFEGTLLPDERRQLNKIFLLDFCNSDSIVSPIDKQETQKSSVLKLLHISFRLIESWEYPSQTLTISNSLMVRNSNQISEKLSDLKVGINLLIKGSQDGVLSLDDNDSQHLPPYGNYYQNLGGDGNVRRNYELLACFKKDMHKVETYLTVAKCRKYLEANCTL
Position of mature hormone in Pre-Hormone protein	188 Residues from position (23-210)
Receptor	N/A
Gene ID	100136734
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 26

HMRbase accession number	10780
Swiss-prot Accession number	P37240 (Sequence in FASTA format)
Description	Thyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the glycoprotein hormones subunit beta family.
Tissue Specificity	Pituitary gland. Higher levels seen in immature fishes than the mature fishes
Post translational modification	N/A
Function	Indispensable for the control of thyroid structure and metabolism. May play some role in the biological processes of the immature fishes
Protein Length	147 Amino acids
Molecular weight	16440
References	1  PubMed abstract 8327483
Domain Name	Cys_knot
Hormone Name	Thyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain)
Mature Hormone Sequence	MCVPTDYTLYEERRECDFCVAINTTICMGFCYSRDSNMKELAGPRFLIQRGCTYDQVEYRTVILPGCPLHANPLFTYPVALSCHCGTCNTDSDECAHKASSGDGARCSKPLRHIYPYPGLNSYIHPN
Position of mature hormone in Pre-Hormone protein	127 Residues from position (21-147)
Receptor	N/A
Gene ID	100136289
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 27

HMRbase accession number	11023
Swiss-prot Accession number	P21993 (Sequence in FASTA format)
Description	Prolactin precursor (PRL).
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the somatotropin/prolactin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	210 Amino acids
Molecular weight	23366
References	1  PubMed abstract 2647439
Domain Name	Hormone_1
Hormone Name	Prolactin
Mature Hormone Sequence	IGLSDLMERASQRSDKLHSLSTSLTKDLDSHFPPMGRVMMPRPSMCHTSSLQTPKDKEQALKVSENELISLARSLLLAWNDPLLLLSSEAPTLPHPSNGDISSKIRELQDYSKSLGDGLDIMVNKMGPSSQYISSIPFKGGDLGNDKTSRLINFHFLMSCFRRDSHKIDSFLKVLRCRATKMRPEAC
Position of mature hormone in Pre-Hormone protein	187 Residues from position (24-210)
Receptor	N/A
Gene ID	100136792
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 28

HMRbase accession number	11051
Swiss-prot Accession number	P26351 (Sequence in FASTA format)
Description	Thymosin beta-11.
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Cytoplasm
Developmental Stage	N/A
Similarity	Belongs to the thymosin beta family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length	42 Amino acids
Molecular weight	4820
References	1   Sakai M., Kono T.; "The cDNA sequence of rainbow trout thymosin beta."; Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases. 2  PubMed abstract 1575682 3   Echner H., Yialouris P.P., Haritos A.A., Gruebler G., Voelter W.; "Structure and syntheses of thymosin beta-11 and beta-12."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.751-752, Escom Science Publishers, Leiden (1993).
Domain Name	Thymosin
Hormone Name	Thymosin beta-11
Mature Hormone Sequence	SDKPNLEEVASFDKTKLKKTETQEKNPLPTKETIEQEKQAS
Position of mature hormone in Pre-Hormone protein	41 Residues from position (2-42)
Receptor	N/A
Gene ID	100170202
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 29

HMRbase accession number	11053
Swiss-prot Accession number	P26352 (Sequence in FASTA format)
Description	Thymosin beta-12.
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Cytoplasm
Developmental Stage	N/A
Similarity	Belongs to the thymosin beta family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization
Protein Length	43 Amino acids
Molecular weight	4891
References	1  PubMed abstract 1575682 2   Echner H., Yialouris P.P., Haritos A.A., Gruebler G., Voelter W.; "Structure and syntheses of thymosin beta-11 and beta-12."; (In) Schneider C.H., Eberles A.N. (eds.);Peptides 1992, pp.751-752, Escom Science Publishers, Leiden (1993).
Domain Name	Thymosin
Hormone Name	Thymosin beta-12
Mature Hormone Sequence	SDKPDLAEVSNFDKTKLKKTETQEKNPLPTKETIEQEKQATA
Position of mature hormone in Pre-Hormone protein	42 Residues from position (2-43)
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated

Search Result - 30

HMRbase accession number	11233
Swiss-prot Accession number	O42241 (Sequence in FASTA format)
Description	Progonadoliberin-2 precursor (Progonadoliberin II) [Contains:Gonadoliberin-2 (Gonadoliberin II) (Luteinizing hormone-releasinghormone II) (LH-RH II) (Gonadotropin-releasing hormone II) (GnRH-II)(Luliberin II); GnRH-associated peptide 2 (GnRH-associated peptideII)].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted protein
Developmental Stage	N/A
Similarity	Belongs to the GnRH family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Stimulates the secretion of gonadotropins
Protein Length	86 Amino acids
Molecular weight	9723
References	1   Penlington M.C.; Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases.
Domain Name	N/A
Hormone Name	Gonadoliberin-2
Mature Hormone Sequence	QHWSHGWYPG
Position of mature hormone in Pre-Hormone protein	10 Residues from position (25-34)
Receptor	Q9I986    Detail in HMRbase
Gene ID	100135862
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 31

HMRbase accession number	11500
Swiss-prot Accession number	Q04617 (Sequence in FASTA format)
Description	Corticotropin-lipotropin A precursor (Pro-opiomelanocortin A) (POMC A)[Contains: NPP 1; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 1 (Alpha-MSH 1); Corticotropin-like intermediarypeptide 1 (CLIP-1); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 1 (Beta-MSH 1); Beta-endorphin 1; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	Expressed in sexually active or inactive fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals, and hypothalamus of triploid and ovulated female trout
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	253 Amino acids
Molecular weight	28559
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	NPP  ACTH_domain  Op_neuropeptide
Hormone Name	Lipotropin gamma (Gamma-LPH)
Mature Hormone Sequence	ELGTDDAVYPSLEAGTAEGGEAEGMEGVFSLQEKKDGSYKMNHFRWSGPPAS
Position of mature hormone in Pre-Hormone protein	52 Residues from position (145-196)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136771
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 32

HMRbase accession number	11501
Swiss-prot Accession number	Q04618 (Sequence in FASTA format)
Description	Corticotropin-lipotropin B precursor (Pro-opiomelanocortin B) (POMC B)[Contains: NPP 2; Corticotropin (Adrenocorticotropic hormone) (ACTH);Melanotropin alpha 2 (Alpha-MSH 2); Corticotropin-like intermediarypeptide 2 (CLIP-2); Lipotropin beta (Beta-LPH); Lipotropin gamma(Gamma-LPH); Melanotropin beta 2 (Beta-MSH 2); Beta-endorphin 2; Met-enkephalin].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	N/A
Developmental Stage	Expressed only in sexually active fish.
Similarity	Belongs to the POMC family.
Tissue Specificity	Pituitary and hypothalamus of adult diploid animals
Post translational modification	Specific enzymatic cleavages at paired basic residues yield the different active peptides. Acetylation of beta-endorphin occurs in a tissue-specific manner.
Function	N/A
Protein Length	240 Amino acids
Molecular weight	26719
References	1  PubMed abstract 1448114 2  PubMed abstract 1448114
Domain Name	ACTH_domain  NPP  Op_neuropeptide
Hormone Name	Met-enkephalin
Mature Hormone Sequence	YGGFM
Position of mature hormone in Pre-Hormone protein	5 Residues from position (212-216)
Receptor	Q6QLQ0   Detail in HMRbase    Q6QLQ1    Detail in HMRbase
Gene ID	100136772
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 33

HMRbase accession number	11507
Swiss-prot Accession number	Q91194 (Sequence in FASTA format)
Description	Somatostatin-2 precursor (Somatostatin II) [Contains: [Tyr21,Gly24]-somatostatin-28; [Tyr7,Gly10]-somatostatin-14].
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Oncorhynchus.
Subcellular location	Secreted
Developmental Stage	N/A
Similarity	Belongs to the somatostatin family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Somatostatin inhibits the release of somatotropin
Protein Length	115 Amino acids
Molecular weight	12963
References	1  PubMed abstract 7628684
Domain Name	Somatostatin
Hormone Name	[Tyr7,Gly10]-somatostatin-14
Mature Hormone Sequence	AGCKNFYWKGFTSC
Position of mature hormone in Pre-Hormone protein	14 Residues from position (102-115)
Receptor	Q5G546   Detail in HMRbase    Q5G547    Detail in HMRbase
Gene ID	100136751
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 34

HMRbase accession number	11567
Swiss-prot Accession number	B0M1K7 (Sequence in FASTA format)
Description	Leptin
Source organism	Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Euteleostei;Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae;Oncorhynchus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	171 Amino acids
Molecular weight	18871
References	1  PubMed abstract 18539064
Domain Name	N/A
Hormone Name	Leptin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
Receptor	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Receptor for this Hormone are either unknown or have not yet been curated